Immunochemistry - Turbidimetric Immunoassay Reagents

The diagnostic reagents Good Biotech Corp. manufactures and offers in the field of in-vitro diagnostics include turbidimetric immunoassays (TIA) and latex-enhanced immunoturbidimetric assays (LETIA or LIT). Manufacturing duck antibodies is the leading-edge technique solely owned by Good Biotech Corp.; duck IgY(ΔFc) antibody, undoubtedly, is used as the major component of the Good Biotech Corp.'s immunochemistry assay kits. TIA is a well-established technique for the rapid quantification of analytes based on antigen-antibody reaction. The measurable range for TIA may be extended by amplifying the immunoaggregate formation obtained by attaching the antibody to latex particles, which is termed a LIT method. Most of the existing TIA/LIT kits are suffering from interferences due to the use of mammalian antibodies. However, for all duck IgY(ΔFc) antibody-based immunochemistry assays produced by Good Biotech, a new type of antibody, duck IgY(ΔFc), has been employed in this test system. Without the Fc domain, IgY(ΔFc) will not cross-react with the following factors which are common interferences for immunoassays:

*Complement *HAMA *Human IgG *RF/ASO *Fc receptors etc 

Therefore, duck IgY(ΔFc) antibody is absolutely an ideal choice for developing immunodiagnostics. The sensitivity, precision, and accuracy can be highly improved by using duck IgY(ΔFc) antibody as the material of immunodiagnostic reagents.      

The assay kits made from avian IgY(ΔFc) antibodies are superior to those used of mammalian antibodies because:

 

There is no immunological cross-reactivity between avian and mammalian antibodies

    (greater phylogenetic spread between both species)

They recognize more specific epitopes

They do not bind mammalian biological products, interfering with activated mammalian antibodies

 

Ready to use reagents, liquid format

Highly sensitivity

Excellent precision & accuracy

Wide linearity

No hook effect

Excellent reproductivity

No false-negative results

No reconstitution errors

No sample pre-treatment is necessary

Accurate results in low concentration sample

Shelf life stability ≧3 years at 4℃ after production

 

TIA & Latex-enhanced TIA(LIT) For automated chemistry analyzers

Good Biotech Corp. has received US FDA 510(k) clearance, CE Marking for its diagnostic products, and has obtained Taiwan- IVD GMP certification for the production of assay kit. Good Biotech has been accredited according to ISO 9001/ ISO 13485 standards, to ensure the consistency and quality of our products from lot to lot.